Love the fact you’re considering screen readers here. Even well thought out websites that degrade gracefully in various legacy browsers without support for CSS and Javascript tend to be a little odd and confusing when listening to them in a reader.

Designers should consider that whilst screen readers today offer good support for “helper” phrases such as “list of three items” this can become very, very annoying for the visually impaired audience when heavily used. I believe that in the future these visitors will demand that websites address their needs (fluent, semantic texts) rather than them having to adapt to a visual site (“helper” sentences of the reader that distract a lot from the content, i.e. “I Own A Highlighted In Bold Red End Of Highlighting Cat.”).

Thanks, Kimberly, for the interesting article!