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I have been using Sass and Compass for one year and I never looked back. Sass gives you variables and calculation, compass has a number of abstracted mixins to deal with cross-browser implementations. It takes one line to get a cross-compatible css3 gradient.
Also, it compiles, so you can pass you css stuff to colleagues who don’t want to use sass.
I know some people see Sass as a ‘developer tool’ in a world of designers, but give it a try, your stylesheet will get shorter, faster to maintain and more optimized when loading.