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I’ve yet to see any empirical evidence that “vertical rhythm” applied to this degree has any impact on how well a reader is able to extract signal from the noise of the page.
Meanwhile, I’ve seen many, many examples of mis-applied “vertical rhythms” resulting in squashed headings where the underlning on a link impinges on the text below. Which just looks clunky.
When you’ve got something other than an aesthetic opinion from the margins — maybe some actual data — then I’ll be interested in expending the effort needed to support real vertical rhythm. Until then, I just don’t see how it’s cost-effective.